Simulated Bile Juice or Artificial Bile Fluid (BZ263)

This simulated fluid is only used in the field of scientific research and For in vitro use only.

Pack Size: 100 mL, 200 mL, 500 mL, 1000 mL

pH is 7.50 – 8.05 (can be customized on the request as per the customer’s project requirement)

Validity: 6 months

Transportation and storage: transportation at room temperature, storage at 2-8 ℃.

Simulated Bile Juice Features & Notes:

1. Simulated Bile Juice is a sterile solution and can be used directly.
2. Simulated Bile Juice Fluid, stored at 4 degrees, transported at room temperature.
3. This Simulated Bile Juice is limited to the scientific research of professionals, and cannot be used for clinical diagnosis or treatment, and cannot be used for food or medicine, and cannot be stored in ordinary houses.
4. For your safety and health, please wear a lab coat and disposable gloves.

Bile or gall acts to some extent as a surfactant, helping to emulsify the lipids in food. Bile salt anions are hydrophilic on one side and hydrophobic on the other side; consequently, they tend to aggregate around droplets of lipids (triglycerides and phospholipids) to form micelles, with the hydrophobic sides towards the fat and hydrophilic sides facing outwards. The hydrophilic sides are negatively charged, and this charge prevents fat droplets coated with bile from re-aggregating into larger fat particles. Ordinarily, the micelles in the duodenum have a diameter of around 1–50 μm in humans.

The dispersion of food fat into micelles provides a greatly increased surface area for the action of the enzyme pancreatic lipase, which actually digests the triglycerides, and is able to reach the fatty core through gaps between the bile salts. A triglyceride is broken down into two fatty acids and a monoglyceride, which are absorbed by the villi on the intestine walls. After being transferred across the intestinal membrane, the fatty acids reform into triglycerides (re-esterified), before being absorbed into the lymphatic system through lacteals. Without bile salts, most of the lipids in food would be excreted in feces, undigested.